50th International Exhibition of Inventions Geneva 2025

Congratulations to our colleagues for winning six awards—four silver medals and two bronze medals—at the International Exhibition of Inventions Geneva 2025.

The International Exhibition of Inventions Geneva is the largest global exhibition devoted exclusively to inventions. All entries are evaluated by an international jury of 135 specialists. This year’s exhibition featured over 1,050 inventions from 38 countries and regions.

Champion of The Vice Chancellor's Cup of Student Entrepreneurship (VCCE) 2025

The Vice Chancellor's Cup of Student Entrepreneurship (VCCE) award ceremony was held on 12 June 2025. VCCE aims to cultivate entrepreneurship among CUHK students and challenge their creativity. The project, “VIPS-A versatile and Integrated Platform for Skeletal-omics” led by Mr. Zhenkang WEN, Dr. Haozhi ZHANG, Mr. Zhengming SHAN and Mr. Zheyu JIN from our department was recognized as the champion in the finals.

Postgraduate Students Received Professor Charles K. Kao Student Creativity Award (PCKKSCA)

A group of students supervised by Prof. Jerry Xu, Prof. Ling Qin, and Prof. Patrick Yung presented their highly innovative biotechnique for bulk tissue imaging, which turns out with 3D images of satisfactory resolution but much less time than traditional histological staining, and therefore was recognized as the first runner-up of PCKKSCA.

Scoliosis Awareness Month Jun 2025 – Public Seminar on Adolescent Idiopathic Scoliosis (AIS)

CUHK ORT and CUHK Medical Centre hosted a successful public scoliosis seminar with Hong Kong Musculoskeletal Health Foundation and Hong Kong Scoliosis Awareness Group on June 28, 2025, attracting over 180 attendees. The CUHK ORT AIS team and field experts discussed latest scoliosis treatment, with sharing of adjunct treatment including bracing and physiotherapy and coping strategies from psychiatrist, physiotherapy and orthotist. Hong Kong Scoliosis Awareness patient supporting group representatives have also shared their personal experiences. The event featured an exhibition of cutting-edge technologies, including computer navigation and orthotic solutions, and a lively Q&A session, fostering greater public awareness and understanding of scoliosis during International Scoliosis Awareness Month.

4th International Conference on Fragility Fracture (ICFF):
Managing Fragility Fractures and Translating Research into Practice

A 1.5-day international event titled “4th International Conference on Fragility Fracture (ICFF): Managing Fragility Fractures and Translating Research into Practice” was successfully organized on 16-17 May 2025.

More than 160 participants attended the international symposium. 8 international well-known speakers delivered excellent talks with great feedback and questions from the floor to provide the knowledge to healthcare professionals (including doctors, nurses, physiotherapists, and occupational therapists) on fragility fractures, osteoporosis and sarcopenia.

The event was also supported by the Fragility Fracture Network Hong Kong SAR.

Start-up Mag Med Biotech Joined CUHK Shanghai Centre

The Chinese University of Hong Kong (CUHK) held its 2025 Shanghai Centre Announcement Meeting on 27 May. With the mission to develop the next generation of magnesium-incorporated medical devices, Mag Med Biotech, represented by Prof. Jiankun XU and Dr. Haozhi ZHANG, was invited to officially begin its incubation at CUHK’s Innoport@Shanghai, a technology incubation hub in the city.

Multiomics profiling of cellular senescence in aging human skeletal muscle uncovers Maraviroc as a senotherapeutic approach for sarcopenia

Prof. Huating Wang, collaborating with Prof. Tim-yun Ong and Prof. Sun Hao (CUHK-Shenzhen), have recently published exciting research in Nature Communications. Their findings unlocked crucial insights into how cellular senescence drives skeletal muscle aging, paving the way for potential new treatments for sarcopenia.

As we age, skeletal muscle declines in mass, strength, and function. While cellular senescence, where cells stop dividing and secrete harmful factors, is implicated, its exact role in muscle aging has been unclear. In this study, using cutting-edge single-nucleus multi-omics technology, Prof. Wang’s team revealed increased cellular senescence in aging human skeletal muscle. They demonstrated the heterogeneity and dynamics of cellular senescence and uncovered how the senescent cells drive muscle aging through secreting SASP factors. Furthermore, their findings uncovered a novel senotheraupeutic target and a potential small molecule drug, Moroviroic for suppressing senescence and delaying muscle aging. Moreover, the study has also identified upstream transcription factor (TF) regulators of cellular senescence and dissected how one TF, JunB orchestrates SASP production. This work provides the first cellular senescence atlas in aging human muscle and establishes knowledge foundation for developing therapeutic strategies targeting sarcopenia. Dr. Yang Li and Dr. Chuhan Li are the co-first authors of this paper. The link to this publication is
https://www.nature.com/articles/s41467-025-61403-y.

Six Projects Successfully Funded by General Research Fund (GRF) and Innovation and Technology Fund (ITF)

Our department has successfully obtained support from the RGC and ITC for six research projects. Congratulations are in order for our principal investigators and their project teams!

PI: - Prof. Wang Huating

Funding body: - GRF

Title of project: - Functional study of JunB in skeletal muscle regeneration -a tale of muscle stem cell-niche crosstalk

Funding amount: - HK$1,381,520

PI: - Prof. Pauline Lui Po-yee

Funding body: - GRF

Title of project: - Injectable hydrogel loaded with damage-seeking AP1122 Protein - an innovative targeted solution for degenerative tendinopathy

Awarded amount: - HK$1,208,830

PI: - Prof. Lin Sien

Funding body: - GRF

Title of project: - Elucidating skeletal interoception circuits in distraction osteogenesis

Awarded amount: - HK$1,295,175

PI: - Prof. Elvis Chui Chun-sing

Funding body: - ITF

Title of project: - AI-driven robotic navigation solution for automatic bone defect reconstruction, prosthesis design and surgical intervention

Awarded amount: - HK$4,353,850

PI: - Prof. Elvis Chui Chun-sing

Funding body: - ITF

Title of project: - Augmented reality navigation system enhanced by artificial intelligence for Anterior Cruciate Ligament reconstruction surgery

Awarded amount: - HK$1,999,907

PI: - Prof. Elvis Chui Chun-sing

Funding body: - ITF

Title of project: - Artificial intelligence-assisted bone density detection system based on chest X-rays

Awarded amount: - HK$1,999,562

[From left] - Prof. Wang Huating, Prof. Pauline Lui Po-yee, Prof. Lin Sien and Prof. Elvis Chui Chun-sing