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CONTACT INFORMATION
Office : (852) 3505-3308
Email : jiankunxu@cuhk.edu.hk
ACADEMIC ENGAGEMENT
Postgraduate teaching:
MPhil/PhD in Orthopaedics & Traumatology
ORCID: 0000-0003-0280-9930 |
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Professor XU Jiankun, Jerry 許建坤 |
Bachelor of Clinical Medicine (SUMC), Master of Orthopaedics (SUMC), PhD (CUHK)
Assistant Professor
助理教授
BIOGRAPHY
As an assistant Professor in ORT and deputy director of the Areas of Excellence Centre for Musculoskeletal Degeneration and Regeneration, Dr. Xu mainly focuses on developing innovative biomaterials to enhance tendon, bone, and cartilage regeneration. With a clinical training background in Orthopaedics and an in-depth understanding of musculoskeletal disorders, Dr. Xu has published over 100 peer-reviewed SCI articles (total impact factor > 700, cumulative citations > 5500, H-index 40) in regenerative medicine. His representative works include original publications in Nature Medicine (2016), Advanced Materials (2024, 2025), Materials Today (2022, 2023), Journal of Clinical Investigation (2024), Nature Communications (2021), Advanced Functional Materials (2023), Biomaterials (2021, 2022, 2024, 2025), and ACS Central Science (2019).
Above efforts have earned Dr. Xu numerous academic awards, including Webster Jee Young Investigator (2016), Savio L.Y. Woo Young Researcher (2018), COA Basic Research Award (2024), COA Innovation & Translation Award (2025), Research Excellence Award (Faculty of Medicine, 2022) from CUHK, and Tigris Education Fund. As principal investigator, Dr. Xu has been supported by the General Research Fund (GRF), the National Natural Science Foundation of China (NSFC, Young Scholar & General Schemes), the Health & Medical Research Fund, Direct Grants from CUHK, and other regional grants. In addition, Professor Xu has founded three start-ups (Targene Biotech, Mag Med Biotech, and HuaMg Perfection), aiming to push forward clinical applications of the self-developed products, with support from the Innovation and Technology Commission of Hong Kong and other external funding.
Dr. Xu is a lifetime member of ICMRS and a founding member of the Sports Medicine Physician Union in the Guangdong-Hong Kong-Macao Greater Bay Area. He also actively supports peer review and serves as a reviewer for many international journals.
EXPERTISE
- Fracture Fixations and Evaluations
- Stem Cell Characterizations and Therapies
- Musculoskeletal Tissue Engineering
SPECIALISED RESEARCH AREAS
- R&D of Biodegradable Implants for Orthopaedic Applications
- Pathologies of Challenging Musculoskeletal Disorders
- Nerve-Vessel-Bone Cross-talks
- Mechanosensitive Factors in Bone, Tendon, and Tendon-Bone Insertions
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SELECTED PUBLICATION
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JX Guo*, H Yao*, L Chang*, WY Zhu, YT Zhang, X Li, BG Yang, BY Dai, X Chen, L Lei, ZY Chen, Y Li, LZ Zheng, WY Liu, WX Tong, YX Su, L Qin#, JK Xu#. Magnesium nanocomposite hydrogel reverses the pathologies to enhance mandible regeneration. Advanced Materials, 37 (2): 2312920 (2025). (IF: 28.9, JCR Q1) |
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YW Zhu*, BY Dai*, SA Zhang, J Liu, SX Xu, WY Liu, X Chen, HZ Zhang, Q Li, FOS Pang, WG Li, CY Wen, L Qin#, JK Xu(#co-corresponding), T Ngai#. Tissue mimetic membranes for healing augmentation of tendon–bone interface in rotator cuff repair. Advanced Materials, 37 (10): 2407358 (2025). (IF: 28.9, JCR Q1) |
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YM An*, LZ Zheng*, SA Zhang, HZ Zhang, YT Zhang, HW Shao, WX Tong, ZY Chen, H Yao, ZK Wen, SX Xu, Y Li, QY Tian, LM Cheng, W Sun, L Qin#, JK Xu#. Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis. Biomaterials, 123428 (2025). (IF: 13.4, JCR Q1) |
| 4. |
ZY Jin, JC Chen, ZM Shan, WY Liu, ZK Wen, HW Shao, TZ Liang, ZY Chen, XS Ren, DH Tan, L Qin#, J Hu#, JK Xu#. Prevalence, risk factors, prediction of robust callus formation and accelerated fracture healing in traumatic brain injury patients: a five-year study. Journal of Orthopaedic Translation, 53, 151-160 (2025). (IF: 7.9, JCR Q1) |
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X Li, TZ Liang, BY Dai, L Chang, Y Zhang, SW Hu, JX Guo, SX Xu, LZ Zheng, H Yao, H Lian, Y Nie, Y Li, X He, Z Yao, WX Tong, XL Wang, DHK Chow, JK Xu(#co-corresponding), L Qin#. Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment. Journal of Clinical Investigation, 134, 10 (2024). (IF: 14.4, JCR Q1) |
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L Chang, Y Luo, WR Li, FF Liu, JX Guo, BY Dai, WX Tong, L Qin#, JL Wang#, JK Xu#. A comparative study on the effects of biodegradable high-purity magnesium screw and polymer screw for fixation in epiphyseal trabecular bone. Regenerative Biomaterials, 11, rbae095 (2024). (IF: 8.1, JCR Q1) |
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NY Zheng, JK Xu (equal-first), YC Ruan, L Chang, XL Wang, H Yao, JL Wang, R Zhang, QY Xue, N Tang, TY Ong, J Schilcher, RJ O'Keefe, L Qin. Magnesium facilitates the healing of atypical femoral fractures: A single-cell transcriptomic study. Materials Today 52, 43-62 (2022). (IF: 25.3, JCR Q1) |
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P Zhao, J Guo, T Jiang, X Xu, S Chen, Z Li, JK Xu (*co-corresponding), G Li#, L Bian#. Vacuolated coacervate mediates the bimodal release kinetics of diverse macromolecular drugs in vivo. Materials Today (2023). (IF: 25.3, JCR Q1) |
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JK Xu, P Hu, X Zhang, J Chen, J Wang, J Zhang, Z Chen, MK Yu, YW Chung, Y Wang, X Zhang, Y Zhang, N Zheng, H Yao, J Yue, HC Chan, L Qin, YC Ruan. Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/beta-catenin signaling. Bioactive Materials 8, 95-108 (2022). (IF: 20.5, JCR Q1) |
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YF Zhang, JK Xu (equal-first), YC Ruan, MK Yu, M O'Laughlin, H Wise, D Chen, L Tian, D Shi, JL Wang, SH Chen, JQ Feng, DH Chow, X Xie, L Zheng, L Huang, S Huang, K Leung, N Lu, L Zhao, H Li, D Zhao, X Guo, K Chan, F Witte, HC Chan, YF Zheng, L Qin. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine 22, 1160-1169 (2016). (IF: 62.4, JCR Q1) |
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