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CONTACT INFORMATION
Office : (852) 3505-1559
Email : louischeung@cuhk.edu.hk
ACADEMIC ENGAGEMENT
Undergraduate teaching:
MBChB Programme
BEng in Biomedical Engineering
Postgraduate supervision:
MPhil/PhD in Orthopaedics & Traumatology
MSc in Musculoskeletal Medicine, Rehabilitation and Geriatric Orthopaedics
MSc in Biomedical Engineering
ORCID: 0000-0003-3247-8255
ResearcherID: J-2150-2018 |
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Professor CHEUNG Wing-hoi, Louis 张颖恺 |
BSc(Hons), PhD, PgCert(Biostatistics)
Professor
教授
Graduate Division Head
研究生部主任
Deputy Director of Musculoskeletal Research Laboratory
骨关节肌肉研究实验室副主任
Deputy Director of MSc in Musculoskeletal Medicine, Rehabilitation and Geriatric Orthopaedics Programmes
骨关节医学、康复及老年骨科理学硕士课程副主任
Academic Appointment: Chairperson, Animal Experimentation Ethics Committee, CUHK
学术委任: 香港中文大学动物实验伦理委员会主席
BIOGRAPHY
Professor Cheung is graduated as PhD in Department of Orthopaedics & Traumatology, CUHK in 2000 and joined as academic staff in 2005. He is also a Programme Committee Member of Biomedical Engineering Programme, Faculty of Engineering, CUHK and Member of Management Committee on the Laboratory Animal Services Centre. He serves as reviewers for AO Foundation and Annual Meeting of Orthopaedic Research Society (ORS); meanwhile, he is editorial board members of 7 international journals and ad hoc reviewers of over 50 professional journals. He is an active member of ORS, ISFR and ICMRS. He has published over 100 peer-reviewed international articles, 8 book chapters, over 300 conference abstracts and contributes as 1 book editor. He was awarded with Berton Rahn Research Fund of AO Foundation in 2013 and Healthstar Osteoporosis Medical-Research Award (HOMA) in 2020. He also obtains 3 patents (1 PCT and 2 US/China).
EXPERTISE
- Animal Model
- Bone Densitometry
- Histomorphometry
SPECIALISED RESEARCH AREAS
- Osteoporotic Fracture Healing and Sarcopenia
- Mechanical Stimulation
- Biophysical Intervention
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SELECTED PUBLICATION
| 1. |
Long YF, Chow SK, Cui C, Wong RMY, Zhang N, Qin L, Law SW, Cheung WH*. Does exercise influence skeletal muscle by modulating mitochondrial functions via regulating MicroRNAs? A systematic review. Ageing Res Rev. 91:102048, 2023. (IF=13.10) |
| 2. |
Liu C, Wong PY, Chung YL, Chow SKH, Cheung WH, Law SW, Chan JCN, Wong RMY. Deciphering the ‘obesity paradox’ in the elderly: a systematic review and meta-analysis of sarcopenic obesity. Obes Rev. e13534, 2022. (IF=8.90) |
| 3. |
Cui C, Bao Z, Chow SKH, Wong RMY, Welch A, Qin L, Cheung WH*. Magnesium supplementation and low-magnitude high-frequency vibration attenuate sarcopenic muscle through PI3K/Akt/mTOR pathway. Int J Mol Sci. 23(21):12944, 2022. (IF=5.60) |
| 4. |
Long YF, Chow SKH, Cui C, RMY Wong, Qin L, Law SW, Cheung WH*. Regulation of mitochondrial dynamic equilibrium by physical exercise in sarcopenia: a systematic review. J Orthop Translat. 35:37-52, 2022. (IF=6.60) |
| 5. |
Cheung WH*, Hung VWY, Cheuk KY, Chau WW, Tsoi KKF, Wong RMY, Chow SKH, Lam TP, Yung PSH, Law SW, Qin L. Best performance parameters of HR-pQCT to predict fragility fracture – systematic review and meta-analysis. J Bone Miner Res. 36(12):2381-2398, 2021. (IF=6.20) |
| 6. |
Cheng KYK, Chow SKH, Hung VWY, Wong CHW, Wong RMY, Tsang CSL, Kwok T, Cheung WH*. Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis (BIA) validated with DXA. J Cachexia Sarcopenia Muscle. 21(6):2163-2173, 2021. (IF=8.90) |
| 7. |
Liu C, Cheung WH*, Li J, Chow SKH, Yu J, Wong SH, Ip M, Sung JJY, Wong RMY. Understanding the gut microbiota and sarcopenia: a systematic review. J Cachexia Sarcopenia Muscle. 12(6):1393-1407, 2021. (IF=8.90) |
| 8. |
Chui CS, Leung KS, Qin JH, Shi DF, Augat P, Wong RMY, Chow SKH, Huang XY, Chen CY, Lai YX, Yung PSH, Qin L, Cheung WH*. Population-based and personalized design of total knee replacement prosthesis for additive manufacturing based on Chinese anthropometric data. Engineering. 7(3):386-94, 2021. (IF=12.80) |
| 9. |
Wang J, Cui C, Chim YN, Yao H, Shi L, Xu J, Wang J, Wong RMY, Leung KS, Chow SKH, Cheung WH*. Vibration and HMB suppresses intramuscular fat infiltration and adipogenic differentiation in sarcopenic mice. J Cachexia Sarcopenia Muscle. 11:564-77, 2020. (IF=8.90) |
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Qin JH, Chow SK, Guo AY, Wong WN, Leung KS, Cheung WH*. Low magnitude high frequency vibration accelerated cartilage degeneration but improved epiphyseal bone formation in anterior cruciate ligament transection induced osteoarthritis rat model. Osteoarthritis Cartilage. 27(7):1061-7, 2014. (IF=7.00) |
SELECTED AWARDS
| 1. |
学科成就奖: 第十届中国药学发展奖康辰骨质疏松医药研究奖 (HOMA), 2020 |
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壹等奖： 通用型骨科导航手术机器人系统关键技术研发与临床应用。北京市科学技术奖, 2018 |
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Shihao Liu-Xianyi Zhu Memorial Best Paper Award: Activated osteocytes and enhanced mineralization in osteoporotic metaphyseal fracture healing model augmented with cyclic mechanical loading. 9th International Conference on Osteoporosis and Bone Research. Suzhou, China. 2018 |
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Best Paper Award for Associate Member: Influence of sarcopenia on osteoporotic fracture healing in senescence accelerated mouse model. The 36th Annual Congress of Hong Kong Orthopaedic Association. Hong Kong. 2016 |
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Berton Rahn Research Fund Prize Award: AO Foundation, Switzerland. Lima, Peru. 2013 |
RESEARCH TRANSLATION
| 1. |
Low-magnitude high-frequency vibration therapy [licensed for commercialization] - a CDC recommended fall intervention (2023 CDC compendium of Effective Fall Interventions: What Works for Community-Dwelling Older Adults, 4th Edition; https://www.cdc.gov/falls/programs/compendium.html, page 94-95)
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