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CONTACT INFORMATION
Office : (852) 3763-6047
Email : huating.wang@cuhk.edu.hk
WangLab @ CUHK :
https://cuhkwanglab.github.io/
ACADEMIC ENGAGEMENT
Postgraduate teaching:
Advances in Biomedical Sciences
Joint Course for Advanced Study
Postgraduate supervision:
Mphil/PhD in Orthopaedics and Traumatology
ORCID: 0000-0001-5474-2905
Scopus Author ID: 9042880700
Google Scholar: o0VJqJ0AAAAJ |
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Professor WANG Huating 王华婷 |
PhD(OSU), BS(NJU, China)
Professor
教授
BIOGRAPHY
Dr. Wang is currently a Professor at Li Ka Shing Institute of Health Sciences, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong. She received her B.S degree in 1996 from Nanjing University, China and majored in Environmental Chemistry. In 1998 she moved to USA to pursue her PhD degree at the Ohio State University (OSU) with the award of a Research Assistantship. She studied Molecular Virology under the mentorship of Dr. Louis Mansky and obtained her PhD in 2004. She then remained at OSU since 2004 for her Postdoctoral training under the mentorship of Dr. Denis Guttridge with the support of a Postdoctoral Researcher Fellowship from The Comprehensive Cancer Center, OSU and later a F32 Postdoctoral Fellowship Award from National Institute of Health, USA. In 2009, after a successful Postdoctoral training, she moved to Hong Kong for an Assistant Professor position at Department of Obstetrics and Gynaecology, Faculty of Medicine, the Chinese University of Hong Kong. She then moved to Department of ORT and was soon promoted to Associate Professor in 2015 and Full Professor in 2020. Since 2004, she has developed life-long interest in studying gene regulatory mechanisms using skeletal muscle cells as a model system. Currently the main focus of her group is to study intrinsic and extrinsic regulation of skeletal muscle stem cells in muscle regeneration, diseases and aging.
SPECIALISED RESEARCH AREAS
- Gene Regulation
- Skeletal Muscle Stem Cell and Regeneration
- Skeletal Muscle Diseases and Muscle Aging
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SELECTED PUBLICATION
| 1. |
Li Y, Li C, Zhou Q, Liu X, Qiao Y, Xie T, Sun H*, Ong M*, Wang H*. (2025) Multiomics mapping and characterization of cellular senescence in aging human skeletal muscle uncovers a novel senotherapeutic for sarcopenia. Nature Communications. 16: 6207. |
| 2. |
Chen X*, Yang F, Zhang S, Guo X, Zhao J, Qiao Y, He L, Li Y, Zhou Q, Ong MT, Kwok CK, Sun Hao*, Wang H*. (2025) DNA G-quadruplex profiling in skeletal muscle stem cells reveals functional and mechanistic insights. Genome Biology. 5;26(1):269. |
| 3. |
Sun Q, Zhou Q, Qiao Y, Chen X, Sun Hao*, Wang H*. (2025) Pervasive RNA-binding protein enrichment on TAD boundaries regulates TAD organization. Nucleic Acids Research. 7;53(1):gkae1271. |
| 4. |
Li Y, Li C, Sun Q, Liu X, Chen F, Cheung Y, Zhao Y, Xie T, Chazaud B, Sun H*, Wang H*. (2025) Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-CCL5 axis. Nature Communications. 03: 1324. |
| 5. |
Zhang Y, Zhao J, Chen X, Qiao Y, Kang J, Guo X, Yang F, Lyu K, Ding Y, Zhao Y, Sun H*, Kwok C*, Wang H*. (2024) DHX36 binding induces RNA structurome remodeling and regulates RNA abundance via m6A reader YTHDF1. Nature Communications. 15: 9890. |
| 6. |
Zhao Y, Ding Y, He L, Zhou Q, Chen X, Li Y, Alfonsi MV, Wu Z, Sun H* and Wang H*. (2023) Multiscale 3D Genome Reorganization during Skeletal Muscle Stem Cell Lineage Progression and Aging. Science Advances. 17;9(7). |
| 7. |
Chen X, Yuan J, Xue G, Campanario S, Wang D, Wang W, Mou X, Liew SW, Umar MI, Isern J, Zhao Y, He L, Li Y, Mann CJ, Yu X, Wang L, Perdiguero E, Chen W, Xue Y, Nagamine Y, Kwok CK, Sun H*, Muñoz-Cánoves P*, Wang H*.(2021) Translational control by DHX36 binding to 5’UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nature Communications. 19;12(1):5043. |
| 8. |
Yu Zhao, Jiajian Zhou, Liangqiang He, Yuying Li, Jie Yuan, Kun Sun, Xiaona Chen, Xichen Bao, Miguel A. Esteban, Hao Sun, Wang H*. (2019) MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation. Nature Communications. 10, 5787. |
| 9. |
Chen F, Zhou J, Li Y, Zhao Y, Yuan J, Cao Y, Wang L, Zhang Z, Zhang B, Wang CC, Cheung TH, Wu Z, Wong CC, Sun H, Wang H*. (2019) YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells. EMBO Journal. 15;38(10). |
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Wang, L., Zhao, Y., Bao, X., Zhu, X., Kwok, Y. K., Sun, K., Chen, X., Huang, Y., Jauch, R., Esteban, M. A., Sun, H., & Wang, H.*. (2015) LncRNA Dum Interacts with Dnmts to Regulate Dppa2 Expression during Myogenic Differentiation and Muscle Regeneration. Cell Research, 5(3):335–350. |
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